396What is the Best Predictor for Vancomycin Nephrotoxicity?
نویسندگان
چکیده
396. What is the Best Predictor for Vancomycin Nephrotoxicity? Kassem Hammoud, MD; Neil Goodloe, MD; Wael Haidar, MD; Michael Brimacombe, PhD; Wissam El Atrouni, MD; Internal Medicine/Infectious Diseases, University of Kansas Medical Center, Kansas City, KS; Cox Health System, Springfield, MO, Uruguay; Adena Health Care, Chillicothe, OH; Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS
منابع مشابه
Comparative Incidence of Nephrotoxicity by Age Group among Adult Patients Receiving Vancomycin
INTRODUCTION Little is known regarding age-related risk of nephrotoxicity during vancomycin therapy after the publication of the 2009 vancomycin consensus guidelines for therapeutic drug monitoring. We sought to evaluate incidence and risk factors for acute kidney injury in three age groups. METHODS Matched cohort study of patients receiving vancomycin, grouped by age: young adults (18-64 yea...
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Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...
متن کاملHow much vancomycin dose is enough for the MRSA infection in pediatric patients with various degrees of renal function?
Today, an increase in vancomycin dose has been proposed to ensure efficacy. However, the risk of nephrotoxicity will increase with the dose. This study was aimed at evaluating the dosage regimens of vancomycin in pediatric patients based on pharmacokinetics/pharmacodynamics (PK/PD) and to optimize dosage individualization. Population pharmacokinetics analysis was performed on 155 Chinese childr...
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Vancomycin susceptibility of methicillin-resistant Staphylococcus aureus has been changed over time and its average minimum inhibitory concentration increased from 1.5 to 1.75 mg/L. A recently published guideline by the American Society of Health Pharmacist recommended a daily dose of 15-20 mg/kg every 8 to 12 hours of vancomycin to achieve a trough concentration between 15-20 mg/L for treatmen...
متن کاملElevated Vancomycin Trough Concentration: Increased Efficacy and/or Toxicity?
Vancomycin susceptibility of methicillin-resistant Staphylococcus aureus has been changed over time and its average minimum inhibitory concentration increased from 1.5 to 1.75 mg/L. A recently published guideline by the American Society of Health Pharmacist recommended a daily dose of 15-20 mg/kg every 8 to 12 hours of vancomycin to achieve a trough concentration between 15-20 mg/L for treatmen...
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2014